
团队负责人
团队成员
郭旭东、严荣国、陈明惠、赵展、陈丽雯、魏文卿
团队简介
本团队主要从事智能化、高性能医疗装备方面的研究,研究方向包括:(1)精密机械设计(含多物理场耦合仿真与组织三维重构);(2)嵌入式智能仪器(硬件/PCB/单片机/树莓派开发及机器人测控);(3)生物医用材料;(4)大数据与AI辅助诊断;(5)模式识别与深度学习算法部署。
团队近10年来主持国家自然科学基金、国家重点研发计划等国家级课题6项,各类省部级课题14项,横向课题22项,总项目经费超过4000万元。发表SCI收录论文100余篇,授权发明专利20余项,部分成果已实现临床转化应用。指导学生参加校定A类竞赛,获省部级以上奖项40余项。
代表性成果
1.科研项目
[1]2024-2027年,国家自然科学基金-面上项目,影像引导下柔性靶器官穿刺机器人的探针定位与形变校正机理
[2]2024-2027年,国家重点研发计划-子课题,高信噪比功能集成探针创制技术研究
[3]2024-2026年,国家自然科学基金-青年基金项目,嵌段共聚物球形胶束溶液中的结晶机制研究
[4]2022-2026年,国家重点研发计划-重点专项,放射治疗装备质量评价技术和临床应用质量保障体系构建(参与)
[5]2022-2025年,国家重点研发计划-子课题,放射治疗设备安全有效性评价方法研究
[6]2014-2016年,国家自然科学基金,OCT超宽带窄瞬时线宽扫频方法研究
[7]2011-2013年,国家自然科学基金-青年基金项目,胶囊状微诊疗装置无线跟踪方法的传感机理研究
[8]2024-2026年,上海市协同创新项目,模块化基本急救关键技术与装备的迭代与产业化
[9]2023-2025年,上海市协同创新项目,平战时环境下便携式X线机关键技术研究与样机制备
[10]2022-2025年,上海张江国家自主创新示范区专项发展资金重点项目,机器人辅助精准肿瘤射频消融系统的研发与产业化
[11]2021-2024年,上海市产业战略关键领域技术攻关生物医药专题项目,超声刀系统的研发与产业化
[12]2021-2024年,上海市市级科技重大专项-子课题,脑机接口关键技术与核心器件
[13]2015-2018年,上海市科委产学研医项目-子课题,iPOCT大数据中心技术平台的建立及研究
[14]2013-2016年,上海市自然科学基金,超宽带窄瞬时线宽扫频方法用于疾病早期诊断OCT研究
2.发明专利
[1]崔海坡,郭旭东,邹最,等;一种多维可调式仿生下肢外骨骼装置,ZL202510223259.0,2025-11-25
[2]郭旭东,赵展,肖建如,等;一种具有多点位自解锁的单驱型胶囊式活检装置,ZL202210493947.5,2025-06-06
[3]崔海坡,张岩,杜科伟,等;一种可调节髌骨复位固定器,ZL202210388342.X,2024-11-26
[4]赵展,郭旭东,杨谷烨莉;基于多轴连杆机构的非同迹式胶囊状活检机器人,ZL202210493922.5,2024-09-24
[5]崔海坡,郭旭东,葛斌,等;一种弱化人体吸收功能的装置,ZL201910065033.7,2024-06-25
[6]郭旭东,严荣国,葛斌,等;一种消化道电子胶囊的数字式定位系统及方法,ZL201810136700.1,2024-05-31
[7]郭旭东,杜奕奇,刘张;基于多卷积神经网络集成学习的小肠内镜图片特征提取方法,ZL202110517771.8,2023-05-02
[8]严荣国,邵泓燃,张瀚文,等;一种基于色标传感器的尿液成分分析装置,ZL202011589034.0,2023-04-21
[9]严荣国,叶君军,赵展;一种流式细胞分析技术的教学实验仪器,ZL202110036120.7,2022-10-14
[10]崔海坡,赵展,丁沫然,等;一种用于人体被动动态平衡训练的驱动装置,ZL202110991609.X,2022-08-05
[11]崔海坡,赵展;一种多态人体平衡训练系统,ZL202110994715.3,2022-04-12
3.科技成果奖
[1]2015,上海市科技进步三等奖
[2]2015,中国机械工业联合会技术发明奖二等奖
4.学术论文
[1] Dual-mode endoscopic probe for optical coherence tomography and plasma ablation. Journal of Innovative Optical Health Sciences, 2026, 19(3).
[2] Exploration and Performance Analysis of Deep Learning Applications in Spermatic Vein Ultrasound Segmentation. Biomedical Physics & Engineering Express, 2026, 12(2), 025041.
[3] An Accelerated Heart Sound Classification Design Based on a Heterogeneous Platform. The Journal of Supercomputing, 2026, 82, 216.
[4] UTMorph: A hybrid CNN-transformer network for weakly-supervised multimodal image registration in biopsy puncture. Medical Image Analysis, 2026, 109, 103938.
[5] Innovative ESCS Bridging System: Enhancing Motor Task-Specific Activation in Spinal Cord Injury. Advanced Materials Technologies, 2026, 11(5), 01055.
[6] Correlation Between Structural Parameters and Piezoelectric Performance of PVDF Heart Sound Sensors. Annals of Biomedical Engineering, 2026.
[7] Dual-modal all-fiber OCT needle probe integrated with FBG for simultaneous imaging and temperature sensing. Optics Express, 2026, 34(5), 7388-7400.
[8] Quantitative evaluation of the thenar skin characteristics of patients with diabetes using optical coherence tomography. Optics Express, 2025, 33(23), 49029-49046.
[9] Subcutaneous depth-selective spectral imaging with muSORS enables non-invasive glucose monitoring. Nature Metabolism, 2025.
[10] An Enhanced Double-Unet Segmentation Framework for the Early Detection of Diabetic Retinopathy. International Journal of Imaging Systems and Technology, 2025.
[11] Assessment of Optical Attenuation and Skin Thickness in Type 2 Diabetes Mellitus Patients Using Optical Coherence Tomography. Journal of Biophotonics, 2024, 17(12), e202400267.
[12] Finite element comparison of titanium and polyetheretherketone materials for mandibular defect reconstruction. American Journal of Translational Research, 2024, 16(10), 6097.
[13] Cascade-EC Network: Recognition of Gastrointestinal Multiple Lesions Based on EfficientNet and CA_stm_Retinanet. Journal of Imaging Informatics in Medicine, 2024, 37(5), 7-11.
[14] Automated classification of ulcerative lesions in small intestine using densenet with channel attention and residual dilated blocks. Physics in Medicine & Biology, 2024, 69(1), 055017.
[15] Detection of Multiple-heated Edible Oil Based on Fluorescence Spectroscopy and Lifetime. Journal of Applied Spectroscopy, 2022, 89(1), 126-133.
[16] Pose tracking method using magnetic excitations with frequency division for robotic endoscopic capsules. Biomedical Microdevices, 2022, 24(1), 9.
[17] A novel Joint-Net model for recognizing small bowel polyp images. Minimally Invasive Therapy & Allied Technologies, 2022, 31(5), 712-719.
[18] Multiscale dual attention mechanism for fluid segmentation of optical coherence tomography images. Applied Optics, 2021, 60(23), 6761-6768.
[19] Miniaturized all fiber probe for optical coherence tomography and pH detection of biological tissue. Journal of Biophotonics, 2021, 14(2).
[20] A miniaturised system for the measurement of the refractive index of sub-microlitre liquid. Chinese Optics Letters, 2019, 17(4), 041201.
[21] Automated polyp segmentation for colonoscopy images: A method based on convolutional neural networks and ensemble learning. Medical Physics, 2019, 46(12), 5666-5676.
[22] A novel and reproducible release mechanism for a drug-delivery system in the gastrointestinal tract. Biomedical Microdevices, 2019, 21(1), 25-33.
[23] Modelling and solving the position tracking problem of remote-controlled gastrointestinal drug-delivery capsule. Biomedical Signal Processing and Control, 2018, 39, 213-218.

